Therapeutic Area | Formulary Choices | Cost for 28 (unless otherwise stated) | Rationale for decision / comments |
---|---|---|---|
3.7 Mucolytics | |||
Mucolytics | Carbocisteine | 375mg capsules: £5.08 (120) 250mg/5ml liquid: £8.55 (300ml) 750mg/10ml oral solution sachets £3.85 (15 x 10ml) | Do not routinely use to prevent exacerbations. Carbocisteine can be considered in patients with COPD with copious or tenacious sputum. Trial carbocisteine 750mg tds for 4 weeks and stop if ineffective. If effective reduce to bd. Dose: initially 2.25g daily in divided doses, then 1.5g daily in divided doses as condition improves. Erdocysteine is non-formulary |
Acetylcysteine (N-acetylcysteine) as NACSYS® | 600mg effervescent tablets. One daily. £5.50 (30) | Please do not use any other brand as at least 5 times the price. Adult use only Acetylcysteine 200mg sachets at tds work out at £337 per month |