See patient information leaflet on Actinic keratoses (British Association of Dermatologists December 2020)

Sunscreens are regarded as drugs when prescribed for skin protection (ACBS) against ultraviolet radiation and/or visible light in abnormal cutaneous photosensitivity causing severe cutaneous reactions in genetic disorders (including xeroderma pigmentosum and porphyrias), severe photodermatoses (both idiopathic and acquired) and in those with increased risk of ultraviolet radiation causing adverse effects due to chronic disease (such as haematological malignancies), medical therapies and/or procedures.

Therapeutic AreaFormulary ChoicesCost for 28
(unless otherwise stated)
Rationale for decision / comments
Antineoplastic drugs, Antimetabolites
as Efudix®
5% cream: £32.90 (40g)First line for Actinic keratosis.
Analgesics, non-steroidal anti-inflammatory drugs
Diclofenac 3% gel
as Solacutan®
3% gel: £36.39 (50g)
Antivirals, immune response modifiers
as Aldara®
5% cream: £48.60 (12 x 250mg sachet)
Anti-neoplastic drugs, protein kinase inhibitor
as Klisyri®
10mg/g ointment: £59.00 (5 x 250mg sachet)